Avaliação da atividade antimicrobiana do extrato hidroalcoólico bruto da casca do Stryphnodendron adstringens (Martius) Coville (Barbatimão)

Abstract

Stryphnodendron adstringens (Martius) Coville is a species native to Brazil, popularly known as barbatimão, used in folk medicine to treat various diseases such as gonorrhea, ulcers, diarrhea, as an anti-inflammatory and healing agent. This work aimed to evaluate the antimicrobial activity of the crude hydroalcoholic extract of the barbatimão shell (EHBB) in concentrations 100, 200 and 300 mg? ML, using the agar diffusion method using two techniques - disk diffusion (Kirby Bauer) and well diffusion, and also by the microdilution method, to determine the minimum inhibitory concentration (MIC) against standardized strains microorganisms (ATCC) and bacterial isolates (IB): Enterococcus faecalis (ATCC-19433), Kocuria rhizophila (ATCC-9341 ), Escherichia coli (ATCC-14948), Neisseria gonorrhoeae (ATCC-49226), Pseudomonas aeruginosa (ATCC-27853), Shigella flexneri (ATCC-12022), Staphylococcus aureus (ATCC-25923), Candida albicans (ATCC-10231) Candida krusei (ATCC-6258), Klebsiella pneumoniae (IB), Pseudomonas aeruginosa (IB), Staphylococcus aureus (IB). The results revealed EHBB antimicrobial activity for all bacteria tested, and in the agar diffusion method, the microbial growth inhibition halos ranged from 8.3 to 25.3 mm. In the CIM method, the extract was able to inhibit microbial growth at concentrations ranging from 70 to 200mg / mL, proving to be more efficient for N. gonorrhoeae, P. aeruginosa and yeasts. The antimicrobial activity of barbatimão suggests the need for further studies in order to isolate the substances responsible for this activity and the performance of toxicological tests to facilitate its use in infectious diseases.